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Diflorasone Systematic (IUPAC) name [17-(2-Acetyloxyacetyl)- 6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16- octahydrocyclopenta[a]phenanthren-17-yl] acetate Identifiers CAS number 1-13-8 ATC code D07AC10 PubChem CID 71414 DrugBank APRD00921 Chemical data Formula C26H32F2O7  Mol. mass 494.525 g/mol Therapeutic considerations Pregnancy cat.  ? Legal status Diflorasone is a corticosteroid that comes in the form of a cream containing diflorasone diacetate. According the drug's maker, E. Fougera & Co., it is used for its anti-inflammatory and anti-itching qualities, like other topical corticosteroids. It is often prescribed for psoriasis and atopic dermatitis, and also for Hailey Hailey Disease (Familial Benign Pemphigus). and is considered to be of greater potency compared to other topical corticosteroids. No long-term animal studies have been done to determine whether diflorasone could have carcinogenic properties. Women who are breastfeeding their newborns should probably not use diflorasone since corticosteroids have been known to appear in breast milk and cause negative effects in a newborn, such as inhibited growth, but little data is available regarding whether topical corticosteroids like diflorasone would be present in great enough quantities to cause harm to an infant. v • d • e Corticosteroids – glucocorticoids and mineralocorticoids (H02) (also A07EA, C05AA, D07, D10AA, R01AD, R03BA, S01BA, S02B, and S03B) Mineralocorticoids (3-one, 4-ene, no FG at 16) Pregnenedione: ALDOSTERONE · 11-DEOXYCORTICOSTERONE · HALOGENATED AT 9: Fludrocortisone Glucocorticoids (3-one, 4-ene, 11-FG, 17-hydroxy) Pregnene CORTISONE Pregnenedione (+20-one) HYDROCORTISONE/CORTISOL# (Hydrocortisone aceponate, Hydrocortisone buteprate, Hydrocortisone butyrate) · Budesonide · Ciclesonide · Deflazacort · Medrysone · Tixocortol · HALOGENATED AT 6: Cloprednol · HALOGENATED, WITH FG AT 16: Halcinonide Pregnadiene (+1-ene) Rimexolone · HALOGENATED, WITH FG AT 16: Flunisolide · Triamcinolone · Amcinonide · Fluocinolone acetonide (Fluocinonide) Pregnadienediol (+21-hydroxy) Prednisone (Meprednisone) · HALOGENATED AT 9: Fluorometholone · HALOGENATED, WITH FG AT 16: Fluocortolone (Clocortolone, Diflucortolone, Fluocortin) · Desoximetasone Pregnadienetriol (+11-hydroxy) Prednisolone# (Methylprednisolone, Methylprednisolone aceponate, Prednicarbate, Prednylidene) · Desonide · HALOGENATED: Fluprednisolone (Difluprednate, Fluperolone) · HALOGENATED, WITH FG AT 16: Dexamethasone# · Betamethasone (Clobetasol, Clobetasone, Diflorasone, Halometasone, Ulobetasol) · Beclometasone · Paramethasone  · Alclometasone · Fluclorolone · Flumetasone · Fluprednidene Pregnatriene (+2-ene) Cortivazol Androstene HALOGENATED, WITH FG AT 16: Fluticasone (Fluticasone propionate, Fluticasone furoate) Other/ungrouped HALOGENATED: Loteprednol · HALOGENATED, WITH FG AT 16: Fludroxycortide · Formocortal · Mometasone furoate Aldosterone antagonists Spironolactone · Eplerenone · Potassium canrenoate · Canrenone Synthesis modifiers Trilostane · Carbenoxolone · Aminoglutethimide · Metyrapone #WHO-EM. ‡Withdrawn from market. Clinical trials: †Phase III. §Never to phase III M: END anat/phys/devp/horm/cell noco(d)/cong/tumr, sysi/epon proc, drug (A10/H1/H2/H3/H5) This dermatologic drug article is a stub. You can help Wikipedia by expanding it. v • d • e